Big Ten Conference Reveals USC 2025 Football Schedule

LOS ANGELES—The Big Ten Conference announced USC's 2025 football schedule, today (Dec. 11).

The Missouri State Bears will visit the Los Angeles Memorial Coliseum to open the 2025 football season on Aug. 30, 2025. While Missouri State is currently in its final year in the Missouri Valley Football Conference (FCS), it will officially join Conference USA for the 2025-26 athletic season, thus making it an FBS program. This will be the first time ever that USC has faced Missouri State.

The Trojans then welcome Georgia Southern of the Sun Belt Conference to Los Angeles on Sept. 6. The Eagles, who are coached by former USC head coach Clay Helton, are another new opponent for the Trojans.

USC opens Big Ten Conference play on the road at Purdue on Sept. 13. The Trojans are 3-1 all-time against the Boilermakers, last facing them in 1998 when USC won 27-17 in the Coliseum. The Trojans then return home to the Coliseum to host Michigan State on Sept. 20. USC is tied 4-4 in its series with Michigan State, last falling to the Spartans 16-17 in the 1990 John Hancock Bowl in El Paso, Texas. The Trojans wrap up the month of September by traveling to Champaign, Ill. on Sept. 27 to challenge the Fighting Illini. USC holds an 11-2 record all-time against Illinois, last defeating them in the 2008 Rose Bowl 49-17.

After enjoying a bye-week on Oct. 4, USC hosts Michigan in the Coliseum on Oct. 11. The Trojans lead 6-5 all-time in their series with the Wolverines, most recently falling to them 24-27 in Ann Arbor, Mich. in 2024. Michigan has not played in the Coliseum since 1957, when the Wolverines defeated the Trojans 16-6. USC then travels to South Bend, Ind. to challenge Notre Dame on Oct. 18. The Trojans are 37-52-5 all-time against the Fighting Irish (not including Troy's 2005 victory that was later vacated due to NCAA penalty;  original record: 38-52-5). USC will then take its second bye of the season on Oct. 25 to prepare for its final five-game stretch of the regular season.

USC will kick off the month of November with a trip to Lincoln, Neb. to challenge the Cornhuskers on Nov. 1. USC is 5-0-1 against Nebraska and is 2-0 versus the Cornhuskers on the road. The Trojans return to Los Angeles to host Northwestern on Nov. 8. USC remains undefeated against the Wildcats boasting a 5-0 record, having last faced them in 1956 Rose Bowl where the Trojans secured a 41-32 victory. Another home game awaits the Trojans as USC welcomes Iowa to the Coliseum on Nov. 15. USC is 7-3 all-time against the Hawkeyes, most recently falling to them 24-39 in the 2019 Holiday Bowl. A familiar road trip looms as the Trojans travel north to Eugene, Ore. to take on the reigning Big Ten champions, the Oregon Ducks on Nov. 22. USC holds a 38-23-2 all-time lead in its series with Oregon (not including 1 win vacated due to NCAA penalty; original record: 39-23-2), last falling to the Ducks 27-36 in in Autzen Stadium 2023. USC wraps Big Ten play by challenging crosstown rival UCLA on  Nov. 29 at the Coliseum. USC leads its series with UCLA, 51-34-7 (not including Troy's 2004 and 2005 victories that were vacated due to NCAA penalty; original record:  53-34-7).

The 2025 season will conclude with the annual Big Ten Football Championship Game on Dec. 6, which will feature the top two teams in the overall conference standings at the end of the regular season, with the winner earning the Big Ten Championship. Tiebreaking procedures will be announced at a later date.

Trojan fans interested in purchasing tickets for USC's 2025 season can visit https://usctrojans.com/2025deposits for more information.

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Big Ten Conference Reveals USC 2025 Football Schedule

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