- Quarterback Mark Sanchez (New York Jets) completed 17-of-30 passes for 171 yards and 2 touchdowns in the Jets' win. Sanchez also rushed 4 times for 10 yards and 1 touchdown.
- Quarterback Matt Cassel (Kansas City Chiefs) completed 14-of-18 passes for 90 yards and 2 touchdowns in the Chiefs' 34-14 loss to Philadelphia.
- Quarterback Carson Palmer (Cincinnati Bengals) completed 20-of-37 passes for 183 yards and 1 touchdown in the Bengals' 23-20 win over Pittsburgh.
- Wideout Steve Smith (New York Giants) led the team with 7 receptions for 63 yards and 1 touchdown in the Giants' 24-0 win over Tampa Bay.
- Tailback LenDale White (Tennessee Titans) rushed 7 times for 27 yards and 1 touchdown in the Titans' 24-17 loss to the Jets.
- Linebacker Brian Cushing (Houston Texans) led the team with 8 tackles in the Texans' 31-24 loss to Jacksonville.
- Tailback Reggie Bush (New Orleans Saints) carried the ball 13 times for 64 yards and caught 3 passes for 17 yards in the Saints' 27-7 win over Buffalo.
- Linebacker Keith Rivers (Cincinnati Bengals) led the team with 8 tackles in the Bengals' win.
- Linebacker Rey Maualuga (Cincinnati Bengals) had 5 tackles in the Bengals' win.
- Quarterback Matt Leinart (Arizona Cardinals) completed 2-of-2 pass attempts for 7 yards in mop-up duty at the end of the Cardinals' 31-10 loss to Indianapolis.
- By Ricky Cambier, USCRipsIt student assistant
